HCC Academy

Cryotherapy / Cold Applications

Cryotherapy is a treatment method that specifically uses cold to address ailments and injuries.

Cryotherapy (from the Greek “kryos” = “cold”) is a therapeutic method that specifically uses cold to treat complaints and injuries. There are various forms of cryotherapy, from local applications (e.g., ice packs) to whole-body cold therapy (in specialized cryo chambers). The therapeutic effects are based on the reduction of skin and tissue temperature, which leads to a series of physiological changes in the body.

Mechanism of Cryotherapy

The effect of cryotherapy is based on the targeted cooling of the tissue, which triggers several reactions in the body:

  • Vasoconstriction

    The cold leads to a narrowing of the blood vessels (vasoconstriction), which reduces blood flow to the affected area. This decreases swelling and inhibits inflammation.

  • Pain Relief

    Cold blocks the nerve transmission of pain signals. By reducing the nerve conduction speed, the perception of pain can be diminished.

  • Anti-inflammatory

    By reducing blood flow and slowing down metabolism in the cooled area, inflammatory processes are suppressed. This is particularly beneficial for acute injuries or chronic inflammations.

  • Increased Endorphin Production

    Whole-body cryotherapy involves a massive exposure to cold on the body, which promotes the release of endorphins. These natural "happiness hormones" can not only alleviate pain but also enhance overall well-being.

  • Improvement of Recovery

    Cold stimulates tissue regeneration by supporting the formation of new cells and relieving muscle tension. This is particularly helpful for athletes to recover faster.

Application Examples of Cryotherapy

Cryotherapy is used in various areas of medicine and well-being:

  • Sports Medicine

    Athletes use cryotherapy after intense training sessions or injuries to relieve muscle pain, reduce swelling, and shorten recovery time. Whole-body cryotherapy is particularly popular, utilizing temperatures as low as -110°C in special cold chambers for a short duration.

  • Orthopedics and Rheumatology

    Patients with inflammatory conditions such as arthritis, rheumatism, or tendonitis benefit from cold therapy. The inflammatory processes in the joints are slowed, and the pain decreases.

  • Dermatology

    In dermatology, cold is used to remove unwanted tissue such as warts or scars. The so-called cryosurgery employs liquid nitrogen to precisely freeze and eliminate skin changes.

  • Neurology

    People with neurological conditions such as multiple sclerosis (MS) use cold therapy to relieve muscle tension. Studies indicate that cold can reduce muscle spasticity and improve mobility.

  • Aesthetic Medicine

    Cryotherapy is also used in cosmetics, for example, for cryolipolysis. In this process, fat cells are destroyed by cold, which is utilized as a non-invasive method for fat reduction.

  • Mental Health and Well-being

    Whole-body cryotherapy has proven to be an effective complementary treatment for chronic pain caused by subliminal inflammation, migraines, depression, anxiety disorders, and stress management. The cold stimulates improved endorphin release, which can have a mood-enhancing effect.

Benefits of Cryotherapy

Cryotherapy offers numerous benefits, making it a valuable therapeutic tool:

  • Pain Relief Without Medication

    Since cold directly affects pain perception, cryotherapy can be used as a natural method to relieve pain without relying on pain medications.

  • Reduction of Inflammation and Swelling

    Acute injuries such as bruises, strains, and sprains greatly benefit from cold treatment, as it effectively reduces swelling and inflammation.

  • Acceleration of Recovery

    Athletes and individuals with chronic injuries use cold to enhance recovery and promote muscle restoration.

  • Increase in Well-Being

    Due to the release of endorphins after cold therapy, many users report an increased sense of physical and mental well-being. Cryotherapy can also be used to treat stress and sleep issues.

  • Non-invasive fat reduction

    Cryolipolysis offers a modern method for fat reduction that does not require surgical intervention. Through targeted cold treatment, fat cells are broken down and eliminated by the body.

Processes of cryotherapy at the cellular, tissue, and biochemical levels

Cold therapy not only works on a macroscopic level (e.g., pain relief and inflammation reduction) but also influences profound processes at the cellular, tissue, and biochemical levels. These physiological changes are crucial for the therapeutic benefits of cold application.

These complex reactions of the body to cold are key to the numerous therapeutic applications of cryotherapy.

Cellular
level

At the cellular level, cold slows down metabolism, protects cell structure, and triggers apoptosis in extreme cold.

Slowing down cellular metabolism: When exposed to cold, cellular metabolism slows down, leading to a reduced demand for oxygen and nutrients by the cells. Injured cells then have more time to regenerate without further damage.

Apoptosis and cell destruction: At very low temperatures, such as those used in cryosurgery (e.g., wart removal), apoptosis (programmed cell death) is triggered in the target cells.

Change in membrane stability: Cold increases the stability of the cell membrane by reducing the mobility of lipids and proteins. This makes the cell membrane more resilient to external influences, protecting the cells from further damage.

Fabric
level

At the tissue level, cold reduces swelling, regulates blood flow through vasoconstriction and vasodilation, and decreases tissue tension.

Vasoconstriction and Vasodilation: When cold is applied, vasoconstriction (narrowing of the blood vessels) initially occurs. This reduces blood flow to the affected tissue and decreases fluid accumulation in the injured area, which helps to minimize swelling. Following prolonged cold application, reactive vasodilation (widening of the blood vessels) may happen to restore circulation to the tissue and enhance oxygen exchange. This alternation between vasoconstriction and vasodilation facilitates recovery and accelerates healing.

Reduction of Inflammatory Mediators: In inflamed tissue, inflammatory mediators such as prostaglandins, histamines, and cytokines are released, causing pain, swelling, and redness. Cold reduces the release of these signaling molecules, thereby slowing down the inflammatory process and speeding up healing.

Reduction of Tissue Tension: Cold ...

Reduction of tissue tension: Cold can help reduce muscle tone and tissue tension by decreasing spindle activity in muscle fibers. This leads to relief from tension and improves the mobility of muscles and joints.

Biochemical
level

At the biochemical level, cold influences the activity of enzymes and inflammatory mediators, blocks pain signals, and promotes the release of endorphins.

Reduction of Enzyme Activity: At low temperatures, the activity of enzymes involved in the inflammatory response, such as cyclooxygenase (COX), decreases. These enzymes are responsible for the synthesis of prostaglandins, which promote inflammation and pain. Cold inhibits the production of these inflammatory mediators, contributing to pain relief and inflammation reduction.

Impact on Pain Receptors (Nociceptors): Cold has a direct effect on nociceptors, which are responsible for pain perception. The conduction of signals through these nerve fibers slows down, resulting in less intense pain signals being transmitted to the brain. Additionally, cold reduces the release of substance P, a neurotransmitter involved in transmitting pain signals.

Release of Endorphins: A ...

Endorphin Release: A systemic cold application, such as that found in whole-body cryotherapy, can stimulate the release of endorphins. Endorphins are natural painkillers produced by the body that bind to opioid receptors in the brain, reducing the perception of pain and enhancing overall well-being. The increased production of endorphins also improves mood and aids in stress management.

Impact on Oxidative Stress: Cold exposure can reduce oxidative stress in the body by decreasing the production of free radicals. Free radicals are unstable molecules that can damage cells and are involved in inflammatory processes. Reducing oxidative stress through cold therapy protects tissues and promotes cellular regeneration.

Improved Microcirculation: After cold exposure, particularly with whole-body cryotherapy, there is an improvement in microcirculation. This means that the small blood vessels (capillaries) function more efficiently, transporting oxygen and nutrients to the cells more rapidly. This enhances the healing of damaged tissues and improves regeneration.

Conclusion​

Cryotherapy, or cold therapy, is a versatile treatment method used in medicine, sports, and cosmetics. Its therapeutic effects range from pain relief and inflammation reduction to aiding in regeneration. As scientific research continues to explore the positive impacts of cold, cryotherapy is becoming increasingly popular as a complementary or alternative treatment method in various fields.